We study infections during pregnancy and their impact on human placental function. Our goal is to understand how inflammatory responses at the maternal-fetal interface influence pregnancy outcomes.

We leverage unique patient samples—prospectively collected in endemic regions as well as ex vivo human placental explant models—to study these diseases at the molecular level. Thus, we have great potential to bridge the gap between cutting edge molecular techniques, human responses to infection, and clinical outcomes. The long-term goal of our work is to identify novel pathways for therapeutic intervention to prevent the adverse consequences of these perinatal infections.

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